Opana

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Opana (Oxymorphone) is prescribed for the relief of moderate to severe pain and also as a preoperative drug to mitigate worry, maintain anesthesia and as an obstetric pain reliever.

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Description

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Opana is an Oxymorphone powerful semi-synthetic opioid analgesic (painkiller). The duration of pain relief is 3–4 hours for immediate- release tablets and 12 hours for extended-release tablets. It was first manufactured in 1914 in Germany, invented in the USA by Endo Pharmaceuticals in 1955 and introduced in the USA in January 1959 and other countries around the same time. This Oxymorphone is also a minor metabolite of oxycodone, which is formed by CYP2D6-mediated O-demethylation. Here at Discret Pharmacy the best online pharmacy to buy Opana online without any prescription. Guaranteed fast and discreet delivery worldwide. buy Opana online Without Prescription

USES (buy Opana online Without Prescription)

Opana (Oxymorphone) is prescribed for the relief of moderate to severe pain and also as a preoperative drug to mitigate worry, maintain anesthesia and as an obstetric pain reliever. Moreover, can be used to mitigate pain in patients with dyspnea related with acute left ventricular failure and pneumonic oedema. It is practically free of antitussive activity.
Opana tablets are prescribed for the management of chronic pain. And are administered only to patients already on a regular schedule of strong opioids for a long period of time.

 

DOSAGE FORM & STRENGTHS

The 5 mg dosage form is a pink, round, film-coated, biconcave extended-release tablet debossed with an “E”. On one side and a “5” on the other side.

The 7.5 mg dosage form is a gray, round, film-coated, biconcave extended-release tablet debossed with an “E”. On one side and a “7 ½” on the other side.

The 10 mg dosage form is a light orange, round, film-coated, biconcave extended-release tablet debossed with an “E”. On one side and a “10” on the other side.

The 15 mg dosage form is a white, round, film-coated, biconcave extended-release tablet debossed with an “E”. On one side and a “15” on the other side.

The 20 mg dosage form is a light green, round, film-coated, biconcave extended-release tablet debossed with an “E”. On one side and a “20” on the other side.

The 30 mg dosage form is a red, round, film-coated, biconcave extended-release tablet debossed with an “E”. On one side and a “30” on the other side.

The 40 mg dosage form is a light yellow to pale yellow, round, film-coated. Biconcave extended-release tablet debossed with an “E” on one side and a “40” on the other side.

OVERDOSAGE (buy Opana online Without Prescription)

Clinical Presentation
Acute overdosage with oxymorphone is manifested by respiratory depression, somnolence progressing to stupor or coma, skeletal muscle flaccidity. Cold and clammy skin, constricted pupils, and, sometimes, pulmonary edema, bradycardia, hypotension, and death. Marked mydriasis rather than miosis may be seen due to severe hypoxia in overdose situations. buy Opana online Without Prescription

Treatment of Overdose

In case of overdose, priorities are re-establishment of a patent and protected airway and institution or controlled ventilation if needed. Employ other supportive measures (including oxygen, vasopressors) in the management of circulatory shock and pulmonary edema as indicated. Cardiac arrest or arrhythmias will require advanced life support techniques.

The opioid antagonists, naloxone or nalmefene, are specific antidotes to respiratory depression resulting from opioid overdose. Opioid antagonists should not be administered in the absence of clinically significant respiratory or circulatory depression secondary to oxymorphone overdose. Such agents should be administered cautiously to patients who are known, or suspected to be, physically dependent on OPANA ER. In such cases, an abrupt or complete reversal of opioid effects may precipitate an acute withdrawal syndrome. Buy Opana online Without Prescription

The duration of reversal would be expected to be less than the duration of action of oxymorphone in OPANA ER. Carefully monitor the patient until spontaneous respiration is reliably re-established. OPANA ER will continue to release oxymorphone adding to the oxymorphone. Load for up to 24 hours after administration, necessitating prolonged monitoring. Response to opioid antagonists is suboptimal or not sustained, additional antagonist should be given as directed in product’s prescribing information.

In an individual physically dependent on opioids, administration of an opioid receptor antagonist may precipitate an acute withdrawal. The severity of  withdrawal produced will depend on the degree of physical dependence and the dose of the antagonist administered. If a decision is made to treat serious respiratory depression in the physically dependent patient. Administration of the antagonist should  begun with care and by titration with smaller than usual doses of the antagonist. Buy Opana online Without Prescription

SIDE EFFECTS

This drug is highly addictive as with other opioids and can lead to chemical dependence and withdrawal.

Minor Side Effects

Some oxymorphone side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects.

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Additional information

Opana

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